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Abstract

Objective: To observe the effect of modified ultrafiltration on hemodynamics of pediatric patients.
Study Design: A descriptive cross-sectional study.
Place and Duration of Study: Pediatric Cardiac Surgery department, AFIC/NIHD Rawalpindi, from Jun 2019 to Dec 2019.
Methodology: A total of 60 pediatric patients were included undergoing open-heart surgery with cardiopulmonary bypass, having age ≤6 years and weights ≤15kg. To assess hemodynamics parameters observed were pre modified ultrafiltration and post modified ultrafiltration measurements of haemoglobin level, systolic pressure, diastolic pressure, central venous pressure and the number of transfusions given after off-bypass. The data was entered and analyzed in SPSS-23.
Results: The pre-operative mean Hb level of the 60 sampled patients was 12.08 ± 2.89 g/dl. The findings taken pre modified ultrafiltration and post modified ultrafiltration of haemoglobin level was (9.91 ± 0.91 g/dl and 13.09 ± 1.38 g/dl, p<0.05) after an average filtration of 370.83 ± 66.56 ml of the filtrate. The mean of systolic pressure was (61.3 ± 2.01 mmHg and 70.68 ± 1.76 mmHg, p<0.05), diastolic pressure was (49.95 ± 1.35 and 59.7 ± 6.85, p<0.005), Central Venous Pressure was (10.07 ± 1.18 and 9.9 ± 1.09, p>0.005) compared pre modified ultrafiltration and post modified ultrafiltration respectively.
Conclusion: The study concluded that modified ultrafiltration has a significant impact on haemoglobin levels after bypass, decreases the allogenic transfusions and also improve the hemodynamics of the patient.