DefinePK

Abstract

The use of multiple strains of probiotics and multi-enzymes has been shown to enhance growth and immune function in poultry production. This study evaluated the effects of a LACTISAR (LACT), which contains probiotics and enzymes, compared to antibiotics. A total of 180 healthy one-day-old male chicks were randomly allocated into three dietary groups: (i) basal diet (BSD) with no feed additive, (ii) LACT (BSD + 100g LACTISAR/100 kg feed), and (iii) AGP (BSD + 200 g lincomycin/100 kg feed). Each group was subdivided into six replicates, with 10 birds per replicate. Results indicated that during the starter period, the LACT group showed significant improvements in live weight (LW), average daily gain (ADG), and feed conversion ratio (FCR) compared to the BSD group. During the finisher and overall periods, the LACT group exhibited significant (P< 0.01) improvements in LW, ADG, and FCR when compared to both the BSD and AGP groups. No significant differences in average daily feed intake (ADFI) were observed among all groups (P> 0.05). Furthermore, the weight of immune organs (thymus, spleen, and bursa) was significantly higher (P< 0.01) in the LACT group compared to the BSD group. Additionally, the LACT group demonstrated significantly higher levels of immunoglobulins (IgA, IgG, and IgM) in serum (P< 0.01) compared to the BSD group. Overall, dietary supplementation with LACTISAR (a multi-probiotic and enzyme mixture) enhances both the growth performance and immune response of broiler chickens.