DefinePK

Abstract

Objective: To measure the frequency of high detrusor leak point pressures in patients with detrusor overactivity reporting for urodynamic evaluation.
Study Design: Cross sectional study.
Place and Duration of Study: Study was carried out at AFIRM Rawalpindi, from Oct 2016 to Nov 2018.
Material and Methods: Study subjects were selected after informed consent using non-probability consecutive sampling. Urodynamics study were performed and detrusor leak point pressures were calculated for patients who had detrusor over activity.
Results: A total of 110 patients were included in this study. The gender distribution was 24 female (21.8%) and 86 male subjects (78.2%). The mean age was 42.96 ± 19.85 years. The mean pDet at maximum cystometric capacity (MCC) was 30.85 ± 12.55). Out of 110, 56 subjects (50.9%) experienced involuntary leak during cystometric studies. Out of these, 30 cases (53.57%) had Detrusor Leak Point Pressures (DLPP) higher than 40cm of H2O.
Conclusion: The finding of mean pDet is nevertheless suggestive of low compliance in large number of patients especially in SCI with or without high DLPP. Similarly frequency of dangerous DLPP is also worth concern.