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PRODUCTION OF OXYTETRACYCLINE BY DIFFERENT MUTANTS OF STREPTOMYCES RIMOSUS INDUCED BY DRY AND WET HEAT IN A DATE MEDIUM

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Title: PRODUCTION OF OXYTETRACYCLINE BY DIFFERENT MUTANTS OF STREPTOMYCES RIMOSUS INDUCED BY DRY AND WET HEAT IN A DATE MEDIUM

Authors: N.A BAESHIN , A A ABou- ZEID , A O. BAGHLAF

Journal: Pakistan Journal of Scientific and Industrial Research (Series B: Biological Sciences)

HEC Recognition History
Category From To
Y 2023-07-01 2024-09-30
Y 2022-07-01 2023-06-30
Y 2021-07-01 2022-06-30
Y 2020-07-01 2021-06-30
Y 1900-01-01 2005-06-30

Publisher: PCSIR Scientific Information Centre

Country: Pakistan

Year: 1994

Volume: 37

Issue: 9

Language: English

Keywords: OxytetracyclineMutants of S. rimosusDry and wet heatDate medium.

Categories
Microbiology (14542) Genetics (16287) Biotechnology (6089) Radiation Chemistry (21) Pharmaceutical Science (262)

Abstract

Dry heat was more effective as physical mutagen than wet heat for Streptomyces rimosus. The optimal dose oftemperaturefor inducing auxotrophic mutants in Streptomyces rimosus was 55° under dry treatment conditions. Twomutants only out of 138 dry and wet heat mutants produced higher antibiotic titres than the parent organism.

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