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Abstract

Objectives: To determine the association of increased waist-hip ratio with severecoronary artery disease.Methodology: This case control study was conducted at Department ofCardiology, Jinnah Hospital, Lahore from13th December 2014 to 12th June2015.Male shaving coronary artery disease (stenosis of > 50% in a majorepicardial coronary artery) were included in the study and waist-hip ratio wasdetermined at the time of inclusion into study. Matched controls were taken fromsame population. Waist-hip ratio of more than 0.95 was taken as increasedwaist-hip ratio. Odds ratio was calculated to determine the association ofincreased waist hip ratio with severe coronary artery disease.Results: A sample of 360 including 180 in each cases and control groups wereincluded with mean age of 41.62 ± 2.749 ranging from 35 to 45 years of age.Odds ratio (OR) for increased Waist/Hip ratio>0.95 among cases and controlswas 1.93 (p < 0.028). Stratification of Waist/Hip ratio > 0.95 with currentsmokers, 147 (88.6%) among cases were currently smoking with Waist / Hipratio > 0.95 and 134 (8.2%) among controls that were currently smoking hadWaist / Hip ratio>0.95. (OR=1.905, p=0.037).Conclusion: The study concluded that coronary heart disease risk increases withincrease waist/hip ratio and is further augmented by smoking.Key Words: Coronary artery disease, Myocardial infarction,Waist/Hip ratio.