DefinePK

Abstract

Objective: The aim of our study was to determine the frequency of metabolicsyndrome (MS) and to evaluate the distribution of its components in patients withacute coronary syndrome (ACS) among Pakistani adults.Methodology: This descriptive cross sectional study was conducted in Divisionof cardiovascular medicine and interventional Cardiology, Allama Iqbal MedicalCollege/Jinnah Hospital, Lahore from October 2011 to December 2011. Patientsof either gender and from 20 to 75 years of age admitted with ACS via emergencydepartment were recruited after an informed consent. Overall frequency ofmetabolic syndrome was evaluated in these patients. In addition frequency ofindividual components of metabolic syndrome as risk factor for acute coronarysyndrome was also calculated. Data was analyzed in SPSS version 17.Results: The metabolic syndrome was present in 32% of patients and was morefrequent A total of 350 patients with acute coronary syndrome were studied inmen than women (75% vs. 25%). The most frequent component of metabolicsyndrome as a risk factor for ACS was hypertension seen in 52.6 % patients,followed by diabetes mellitus in 42.8%, abdominal obesity in 41.2%, hypertriglyceridemia in 40.0% and low HDL in 31.7 % of patients.Conclusion: Metabolic syndrome has high frequency in patients with acutecoronary syndrome, especially in men. The most frequent components areHypertension and Diabetes