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Abstract

Objective: To determine the role of visual quantification of Tc-99m MIBI myocardial perfusion SPECT in left bundle branch block as compared to coronary angiography findings. Study Design: Prospective randomized controlled trial.Place and Duration of Study: Department of Nuclear Medicine, Armed Forces Institute of Pathology and Armed Forces Institute of Cardiology/National Institute of Heart Diseases; Rawalpindi: Pakistan from 1st Sep 2016 to 31st Jan 2017.Material and Methods: Thirty six patients with complete left bundle branch block and coronary angiography done within past 4 months were included in our study. Patients were divided in three groups on the basis of coronary angiographic findings. Six patients (4 males and 2 females) have normal LAD on coronary angiography, 18 (11 males and 7 females) have less than 50% LAD disease and 12 (9 males and 3 females) have more than 50% LAD lesions. Gated and non-gated pharmacological stress with adenosine myocardial perfusion SPECT was carried out in 1-day rest-stress protocol.Results: There was no significant difference in the baseline data among all these three groups. Mean left ventricular ejection fraction (LVEF) values were lower in moderate LAD Disease group as compared to other two groups (42 ± 12.4 vs 58 ± 9.2 and 60.6 ± 10.6), left ventricular end diastolic volume (LVEDV) and left ventricular ..............Conclusions: Visual quantification of myocardial perfusion scan images is not only simple and easy way of myocardial assessment in LBBB patients but its results are statistically significant when compared with coronary..........