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Abstract

Objective: To evaluate the management and in-hospital outcomes of the patients of infective endocarditis in tertiary cardiac care hospital.Study Design: Descriptive cross-sectional study.Place and Duration of Study: Adult Cardiology Departments of AFIC /NIHD from 1st August 2013 till 31stAugust 2015.Material and Methods: Eighty Four patients with infective endocarditis were included in the study using consecutive sampling technique. Infective endocarditis registry by R & D Department was used as a data collection tool.Results: There were total 84 patients with infective endocarditis, out of which 51.0% (n= 43) were males and 49.0% (n= 41) were females. Mean age was 36.24 ± 15.3 years and mean BMI was found to be 22.68 ± 3.9. Most patients with infective endocarditis had no heart valve disease 41.6%, followed by patients with rheumatic heart disease 39.2% (n=33). Most prevalent co-morbidity was hypertension 30.6% while most Common symptom of the patients was fever 97.5% (persistent fever 63% and intermittent 34.5%). Vegetations were found in all patients. Blood culture was positive in 51% of patients and the most common organism was streptococcus 72%. Mortality of the infective endocarditis patients was 38% (n=32). Causes of mortality were death after surgery, late Presentation of with Complications, death before surgery, unwillingness for the surgery and death due to other causes. Most common cause of death was late presentations of the patients with complications (19%).Conclusion: Infective endocarditis is a disease with high mortality. Appropriate provision of healthcare facilities, improved health awareness, early diagnosis of infective endocarditis.