DefinePK

Abstract

Objective: Comparison of signal averaged ECG parameters in patients with and without left ventricular hypertrophy.
Study Design: Cohort retrospective study.
Place and Duration of Study: Department of Cardiac Electrophysiology, Armed Forces Institute of Cardiology, Rawalpindi from 11th November, 2014 to 10th November, 2015.
Material and Methods: Sixty-four patients with systemic arterial hypertension were divided into two equal groups on the basis of left ventricular hypertrophy. Patients with acute or old myocardial infarction, diabetes mellitus, cerebrovascular accident, heart failure, structural heart disease, bundle branch block and cardiomyopathies were excluded from the study. DMS 300 4L Holter monitors were used to obtain 3 channel signal averaged ECG recording. cardio scan premium luxury software was used for analysis of signal averaged ECG.
Results: There were 49 (76.6%) males and 15 females (23.4%) with the mean age of 60 ± 11.83 years. The mean values for filtered QRS complex, low amplitude signals and root mean square voltage in patients with and without left ventricular hypertrophy were 118.1 and 98.9 ms, 35.4 and 22.2 ms, 89.9 and 94.4  respectively. The mean values of filtered QRS complex and low amplitude signal were significantly higher in patients with left ventricular hypertrophy as compared to those without the hypertrophy. Whereas, difference between the mean values of root mean square voltage were statistically insignificant.
Conclusion: Signal averaged ECG parameters are significantly deranged in hypertensive patients with left ventricular hypertrophy as compared to those without the hypertrophy.