DefinePK

Abstract

In this issue, Khokhar and colleagues describe their analysis of the HBV small S gene partial sequences and its implications for detection, prevention, and treatment in Pakistani patients, Chaudhary et al., reviewed studies on CYP2D6, its genetic polymorphism, and the brain, Usman and Ghaffar compiled studies on Alzheimer’s disease therapy, and discussed the effects of genetic polymorphisms on its efficacy and safety, Ximenes and her colleagues described their study to determine the certain polymorphisms in CYP2C8 gene in Pakistani population and their frequencies in various ethnic groups, Zulfiqar et al shared their study where they reported a lack of association of CYP2C9 genetic polymorphism with oral squamous cell carcinoma, and Ullah and his colleagues compiled important studies discussing venlafaxine pharmacogenetics and their implications for therapeutic efficacy and adverse effects in major depressive disease patients.