DefinePK

Abstract

smokers and non -smokersMethodology: This cross sectional study of 200 subjects with age 18-25 years was carried out at Karachi basedprivate medical college from August - October 2020. Prior the study ethical approval was taken. Male smokers andnonsmokers were included in the study. Male subjects with pulmonary diseases, cardiovascular diseases and anyother skeletal deformities affecting respiration and females were excluded from the study. Height, weight and BMIwere calculated. FEV6 was recorded by a calibrated digital spirometer following the protocol with three readingsand highest reading was taken for analysisResults: This study was composed of 200 male participants. Of the total study population 83 (41%) were smokersand 117(59%) were non -smokers. Mean age of the study participants was 21.89 ± 4.8years Smokers have lowerFEV6 and FEV1/FEV6 values as compared to non- smokers. Significant difference was observed in mean FEV6 ofsmokers and non-smokers (p- value =0.002). Mean FEV1/FEV6 was also significantly different among smokersand non- smokers (p- value = 0.000*)Conclusion: FEV6 and FEV1/FEV6 values were lower in smokers as compared to non -smokers reflecting decline in lung function.