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Title: Could neutrophil to lymphocyte ratio be a marker in Hashimoto's thyroiditis?
Authors: Erhan Onalan , Mehmet Aslan
Journal: Journal of Pakistan Medical Association
Publisher: Pakistan Medical Association.
Country: Pakistan
Year: 2020
Volume: 70
Issue: 8
Language: English
DOI: https://doi.org/10.5455/JPMA.32518
Keywords: chronic inflammationNeutrophil/lymphocyte ratioHashimoto's thyroiditis
Abstract
Objective: To determine the applicability of neutrophil/lymphocyte ratio as diagnostic and prognostic marker in patients with Hashimoto's thyroiditis.
Methods: The retrospective cross-sectional study was conducted at Elazig Firat University, Elazig, Turkey, and comprised data of Hashimato's thyroiditis patients aged 18 years or more admitted between January 1, 2017, and November 1, 2018. A healthy control group was also included to work as controls. Thyroidstimulating hormone, free triiodothyronine, free thyroxine, anti-thyroid peroxidase, complete blood count, and C-reactive protein results were obtained from patient files for both the cases and the controls, and neutrophil/lymphocyte ratio was computed NLR for both the groups. Data was analysed using SPSS 22.
Results: Of the 477 subjects, 377(79%) were cases with a mean age of 45.3±13.8 years, and 100(21%) were controls with a mean age of 36.6±10.7 (p0.05)
Conclusion: Neutrophil/lymphocyte ratio was found to be an effective low-cost marker in the diagnosis and follow-up of Hashimato's thyroiditis.
Keywords: Hashimoto's thyroiditis, Neutrophil/lymphocyte ratio, Chronic inflammation.
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