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Title: Diet influences levels of plasma lipopolysaccharide (LPS) and its soluble receptor (sCD14) in Saudis
Authors: Suhad Maatoug Bahijri , Ghada Mohammad Ajabnoor , Gehan Abdel-Fattah Hegazy , Anwar Abdullah Borai , Basmah Medhat Eldakhakhny , Lubna Nihad Alsheikh , Steve Mustapha Harakeh
Journal: Journal of Pakistan Medical Association
Publisher: Pakistan Medical Association.
Country: Pakistan
Year: 2020
Volume: 70
Issue: 11
Language: English
DOI: https://doi.org/10.5455/JPMA.28279
Abstract
Objective:This study aimed to investigate the association between serum levels of LPS, sCD14 and hs-CRP, and markers of obesity, and dietary composition of healthy adults residing in Jeddah, Saudi Arabia.
Methods: Apparently healthy adults, aged 18-55 years, were recruited from Jeddah population in a cross-sectional design. Anthropometric measurements, and vital signs were taken using standardized techniques. Serum glucose, cholesterol (TC), triglycerides (TG), high-density lipoprotein- cholesterol (HDL-C), hs-CPR, LPS and sCD14 were assayed, and LDL- cholesterol (LDL-C), and atherogenic index of plasma (AIP) were calculated. Means of estimated variables were compared using t-test or Mann–Whitney U-test for two groups and ANOVA for multiple groups. Chi-square, and Pearson’s correlation coefficient were used to identify association and correlations between studied variables.
Results:Means of TG, LDL-C, and hs-CRP increased significantly in both genders with increasing BMI (p= 0.019, and 0.040 for TG, 0.049, and 0.002 for LDL-C in males and females respectively, and
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