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Title: Epidemiological and clinical correlates of oral squamous cell carcinoma in patients from north-west Pakistan
Authors: Saira , Rawail Ahmed , Sajid Malik , Muhammad Fiaz Khan , Muhammad Rauf Khattak
Journal: Journal of Pakistan Medical Association
Publisher: Pakistan Medical Association.
Country: Pakistan
Year: 2019
Volume: 69
Issue: 8
Language: English
Keywords: PakistanEpidemiologySmokeless TobaccoOral hygieneoral cancerSmokingOral squamous Cell carcinomacase-control
Abstract
EXPRESSION CONCERN: This article titled “Epidemiological and clinical correlates of oral squamous cell carcinoma in patients from north-west Pakistan” is under investigation for post-publication authorship disputes.
Objective: To investigate the association of oral squamous cell carcinoma with demographic variables and oral health indicators.
Methods: The observational case-control study was conducted at the Institute of Radiotherapy and Nuclear Medicine, Peshawar, Pakistan, from November, 2015, to August, 2016.Pathologically confirmed patients with oral cancer represented the cases, while The controls were ethnically and linguistically-matched subjects without any oral pathology. Demographical, clinical and pathological data was taken down to assess variables, risk factors, and oral health indicators. Descriptive statistics and logistic regression modelling were employed for data analysis.
Results: Of the 551 subjects, 341(62%) were males, and 210(38%) were females. Of the total, 276(50.1%) were cases and 275(49.9%) were controls. The mean age of the cases was 55.0}13.4 years and that of the controls was 52.8}14.9 years (p=0.073). Poor oral hygiene, periodontal diseases, material of toothbrush, and no use of mouthwash were significant predictors of oral cancer (p
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