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Bleomycin induced pneumonitis: a case successfully managed with high-dose steroids

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Title: Bleomycin induced pneumonitis: a case successfully managed with high-dose steroids

Authors: Shahid Javed Husain , Ali Bin Sarwar Zubairi , Muhammad Irfan 

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 2007

Volume: 57

Issue: 2

Language: English

Categories
Pulmonology (4511) Steroid Therapy (7) Chemotherapy (151) Case Reports (479) Pharmacology (22872)

Abstract

lntroduction


Bleomycin is a chemotherapeutic agent used in a number of solid organ malignancies.1-3 It accumulates in the skin and lungs resulting in skin ulceration and associated pulmonary toxicity. Its use is somewhat limited due to its significant pulmonary adverse effects with bleomycin induced pnemonitis (BIP) as the commonest and most dreaded complications. The overall incidence of pulmonary toxicity is as high as 10% and it is fatal in 1-2%.3,4We present a case of BIP which was successfully managed by the aggressive use of high dose steroids with complete resolution.

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