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Title: Serum Leptin Levels in Pregnant Pakistani Females: Relationship with Body Mass Index and Placental Weight
Authors: G.R. Lakho , K. Nazir , T. Chundrigar , N. Jabeen , M. A. Qureshi
Journal: Journal of Pakistan Medical Association
Publisher: Pakistan Medical Association.
Country: Pakistan
Year: 2001
Volume: 51
Issue: 1
Language: English
Abstract
Objective: To determine the serum leptin levels in Pakistani pregnant subjects at the time of delivery and to ascertain the relationship between serum leptin levels and related variables (weight, body mass index, placental weight, gestational age, parity) at delivery.
Setting: Lady Dufferin Hospital, and Ziauddin Hospital Karachi.
Methods: Leptin concentration was measured in 110 subjects from venous samples, using Active Human ELISA Kit (DSL-10-23100). Samples were selected according to the availability.
Results: Mean maternal weight, body mass index and placental weight were 64.3 ± 13.8 kg, 27.1± 5.8 kg/m2 and 523.5 ± 90 gm, respectively. Gestational age was 36 - 41 weeks and maternal age was 18 - 35 years. Mean serum leptin level was 27.9 ± 18.1 ng/ml. Serum leptin levels were found to he positively correlated with body weight (r = 0.73, p
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