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Title: Sarcomatoid Variant of Renal Cell Carcinoma
Authors: Muhammad Muzaffar , Sajid Mushtaq , Zahid Latif , Ezra Nigar , Nadira Mamoon
Journal: Journal of Pakistan Medical Association
Publisher: Pakistan Medical Association.
Country: Pakistan
Year: 1997
Volume: 47
Issue: 4
Language: English
Introduction
Sarcomatoid renal cell carcinoma is a rare tumour of the kidney whichaccounts for l%of renal neoplasms inadults and has been reported in ito 6.5% of renal cortical carcinomas in different studies The diagnostic morphological feature of this cancer is the intermingling of typical renal cell carcinoma with a component of sarcomatoid features, comprising of spindle cells without organisation or resembling malignant fibrous histiocytoma or fibrosarcoma4. The prognosis of this highly malignant carcinoma is poor and nephrectomy is ineffective in its management because extra-renal invasion is usually present at the time of diagnosis5. Three cases diagnosed histologically as sarcornatoid renal cell careinoma are presented.
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