DefinePK

Abstract

Introduction


Pnapism is defined as a pathological prolonged painful erection of the penis involving the corpora cavernosa , while the corpus spongiosms and glans penis remain flaccid. Priapism occurs most frequently in men in their 30s and 40s. The erection may or may not be related to sexual stimulation or excitation, although some cases have occured after pro­longed sexual activity1.
Reports published on the aetiology describe diverse factors for this disorde2. Majority of the patients have an idiopathic aetiology. Sickle cell disease, solid tumors, leuke­mia and trauma are reported as known causes. Prolonged sexual stimulation, prostatitis and syphilis are also associated with this disorder. in addition to these conditions, an associa­tion has been well documented between priapism and the ingestion of different medicines. Studies have shown that 15-40% cases of pnapisrn were due to psychotropic drugs. Trazodone, an antide present, is usually considered as the main drug responsible for this problem3 but priapism has also been reported with Chiorpromazine, Fluphenazine, Thioxenthene and Haloperidol4,5. This paper presents a case report where Fluoxetine, caused priapism.