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Efficacy of secnidazole in the Treatment of Intestinal Amoebiasis

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Title: Efficacy of secnidazole in the Treatment of Intestinal Amoebiasis

Authors: Huma Qureshi , Rakhshanda Baqai , Sarwar J. Zuberi , Waquaruddin Ahmed , Sohail Akhtar Qureshi 

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 1994

Volume: 44

Issue: 4

Language: English

Categories
Amoebiasis (4) Pharmacology (22872) Parasitology (2240) Infectious Diseases (12373) Gastroenterology (8625)

Abstract

Introduction


Acute intestinal amoebiasis is common in Pakistan1. Though 5- nitroimidazoles are generally used as the drugs of first choice, but compliance is poor due to its longer treatment course. WHO2 has recommended that the treatment of amoebiasis should be based on a suitable, effective and single dose therapy to avoid the risk of non-compliance. Secnidazole, a long acting nitroimidazole which has a half life of 19 hours3 was therefore, tried as a single dose therapy for non-compli­cated intestinal amoebiasis, to see its efficacy and tolerance.

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