DefinePK

Abstract

Abstract


Sixty-two consecutive episodes of diabetic ketoocidosis (DKA) were studied ot Ago Khon University Hospital, Korochi. Forty-four (71%) were type I ond 18(29%) type II diobetics. Meon age wos 28.1 years ond mean durotion of diobetes 4.1 yeors. Infections were the most common precipitoting factor occounting for 28 episodes (45.2%). Twenty-two potients (35.5%) hod hyperosmolality (serum osmolality> 320 mosmol/L). Mean serum Na+ was 131.7 mmol/L ond K+ 4.6 mmol/L. Twenty-three (37.1%) were hyperkalemic ot presentation with seven patients (11.3%) being comatosed and 35 (56.5%) alert. Mean random blood glucose (RBG) was 624 mg/dl, mean pH 7.09, osmolality 316 mosmol/L and the neurological status correlated statistically significantly with mean RBG, pH and asmalality. A leukemaid response was seen in 83.9% episodes. Mortality rate was 8.0% in patients with DKA managed in this hospital