DefinePK

Abstract

Acute febrile neutrophilic dermatosis is an uncom­mon, dramatic skin disease, occurring predominantly in females aged 30 to 60 years1,2. The principal features of Sweet’s syndrome are fever, peripheral blood leucocytosis, multiple raised asymmetric erythematous sharply marginated, painful cutaneous plaques, dense dermal Infiltrate consisting of mature neutrophils and rapid response to steroid treatment. In the majority of patients it is preceded by upper respiratory infection, tonsillitis or flu-like illness by two to three weeks3, Fever and leucocytosis suggest sepsis but the appearance of rash after one to two days should make one think about this differential.