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Title: CAN DIAGNOSIS OF HELICOBACTER PYLORI BE RAPID AND YET SENSITIVE?
Authors: Ghazala Haq , Waquaruddin Ahmed , Javed Iqbal Kazi , Huma Qureshi , Sarwar J. Zuberi
Journal: Journal of Pakistan Medical Association
Publisher: Pakistan Medical Association.
Country: Pakistan
Year: 1991
Volume: 41
Issue: 5
Language: English
ABSTRACT
Diagnostic accuracy of 5 tests viz.,endoscopy, rapid urease, 24 hours urease, culture and histology, were evaluated in the detection of Helicobacter pylon (H. pylon) infection in 50 patients undergoing upper G.l. endoscopy. Endoscopic evidence of gastritis to predict H. pylon infection was 50% specific and 46% sensitive. Rapid and 24 hours urease test and culture were 100% specific when compared with histology and their sensitivity was 71 %, 62% and 21 % respectively. Of the three 100% specific tests, rapid urease test yields results within 15 minutes; therefore this test being easy, rapid and sensitive should be used for screening of H. pylon infection; followed by histology for further confirmation
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