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A HISTOLOGICAL STUDY OF THE EFFECTS OF NONSTEROIDAL ANTI¬ INFLAMMATORY DRUGS (NSAIDs) ON THE GASTRIC AND DUODENAL MUCOSA

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Title: A HISTOLOGICAL STUDY OF THE EFFECTS OF NONSTEROIDAL ANTI¬ INFLAMMATORY DRUGS (NSAIDs) ON THE GASTRIC AND DUODENAL MUCOSA

Authors: Naheed Moghal , N.A. Jafarey 

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 1989

Volume: 39

Issue: 11

Language: English

Categories
Gastric Mucosa (3) NSAIDs (9) Medicine (22336) Pharmacology (22872) Gastroenterology (8625)

Abstract

Abstract


The effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on the gastric and duodenal mucosa was studied in 53 patients. On endoscopic biopsies, 87% patients showed gastritis and 90% duodenitis. Chronic superficial gastritis was the most frequent lesion in the stomach (49%); and mild duodenitis in the duodenum (54%). The antrum was the most frequently involved site in the stomach. An interesting finding in cases of duodenitis was the presence of dilated intestinal glands plugged with mucus

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