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HEALING AND RELAPSE RATES OF DUODENAL ULCER WITH VARIOUS H2 RECEPTOR ANTAGONISTS

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Title: HEALING AND RELAPSE RATES OF DUODENAL ULCER WITH VARIOUS H2 RECEPTOR ANTAGONISTS

Authors: Waquaruddin Ahmed , Huma Qureshi , Sarwar J. Zuberi 

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 1988

Volume: 38

Issue: 12

Language: English

Categories
Duodenal Ulcer (11) H2 Receptor Antagonists (3) Medicine (22336) Pharmacology (22872) Gastroenterology (8625)

Abstract

Abstract


Retrospective analysis of 119 endoscopically proven cases of duodenal ulcer, treated with Famo­tidin (40 mg),Cimetidine (800 mg) and Ranitidine (300 mg) at bed -time, showed heating rates of 91, 74 and 68%, respectively, at 6 weeks. Twenty patients were followed up for one year on maintenance dose and endoscoped at 3, 6 and 12 months. Despite taking the drug regularly a relapse rate of 14% was seen with Famotjdine and 50% each with Cimetidine and Ranitidine. Though relapse was seen with all three drugs, with or without maintenance, but Famotidine showed better healing and less relapse rate with main­tenance therapy (p

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