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SKIN-REACTIVE PROPERTIES OF DIFFERENT CELLULAR FRACTIONS OF ANIMAL-PASSED C. Jejuni/Coli

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Title: SKIN-REACTIVE PROPERTIES OF DIFFERENT CELLULAR FRACTIONS OF ANIMAL-PASSED C. Jejuni/Coli

Authors: Shahana U. Kazmi , Bob S. Roberson , Norman J. Stern 

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 1987

Volume: 37

Issue: 5

Language: English

Categories
Campylobacter Jejuni/Coli (2) Skin Reactivity (1) Medicine (22336) Microbiology (14542) Immunology (7543)

Abstract

Abstract


Polymyxin B treated cell sonicates, cell-free supernatants and outer membrane proteins were pre­pared from animal-passed, virulence-enhanced strains and original isogenic strains of Cjejuni and tested for dermal toxicity in rabbits. Polymyxin B extracts produced the strongest lesions, but the outer membrane protein from 6 times mouse-passed strains elicited a mild skin reaction. Culture-supernatant did not give any noticeable toxicity, suggesting the presence of insufficient factor required to produce measureable effect. Dermal toxicity clearly differentiated animal-passed strains from unpassed original strains which elicited only a weak response(JPMA 37: 132, 1987).

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