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A Correlative Study of Serum Digoxin Levels with Clinical Tolerance

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Title: A Correlative Study of Serum Digoxin Levels with Clinical Tolerance

Authors: Sher Muhammad Khan Paindakhel , Muhammad Ilyas 

Journal: Journal of Pakistan Medical Association

HEC Recognition History
Category From To
Y 2024-10-01 2025-12-31
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
X 2021-07-01 2022-06-30
X 2020-07-01 2021-06-30
W 2012-07-01 2020-06-30
X 2011-05-13 2012-06-30
Y 1900-01-01 2005-06-30

Publisher: Pakistan Medical Association.

Country: Pakistan

Year: 1981

Volume: 31

Issue: 8

Language: English

Categories
Therapeutic Drug Monitoring (4) Clinical Trials (950) Pharmacology (22872) Internal Medicine (19275) Cardiology (10889)

Abstract

Abstract


In a series of 102 digitalised patients serum digoxin levels (SDL) were determined by radioimmunoassay (RIA). Age categorisation included juveniles (15%), adults (67%) and geriatrics (18%). Clinical categorisation included loading, adequate, inadequate, toxic, and borderline digitalisation groups. The mean SDL in the toxic-group was 3 .93 ng/ml (S.D. 1.40), and in the non-toxic group 1.27 ng/ml (S.D. 0.84). In the toxic group with high SDL, palpitations (39.3%), vomiting (35.7%), nausea (21.5%), anorexia (17.8%) and hiccough (10.7%) were the commonest manifestations of digoxin intolerance

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