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Title: P53 Protein Expression in Epithelial Lining of Odontogenic Cysts: An Immunohistochemical Descriptive Case Study
Authors: Aqib Sohail, Aneela Amjad, Nighat Zahid, Asad Aizaz Chatha, Nauman Rauf Khan, Aamer Iqbal, Bilal Yusuf
Journal: Journal of Gandhara Medical and Dental Sciences (JGMDS)
Publisher: Gandhara University, Peshawar
Country: Pakistan
Year: 2021
Volume: 8
Issue: 3
Language: English
Keywords: Dentigerous cystsOdontogenic cystsOdontogenic keratocystsp53Radicular Cysts
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OBJECTIVES:
The current study was conducted to analyze immunohistochemical appearance of P53 protein in odontogenic cysts.
METHODOLOGY:
Thirty paraffin blocks of confirmed case were prepared to investigate the immunohistochemical appearance of P53 protein.
RESULTS:
Sixteen out of thirty odontogenic cysts (53.3%) showed P53, four out of ten dentigerous cyst (40%) had P53, twelve out of fifteen odontogenic keratocysts (80%) expressed P53 while none of the five radicular cysts (0%) showed P53 protein.
CONCLUSION:
Reclassification of OKC as keratocystic odontogenic tumor was supported by the present study and its findings.
 
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