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Abstract

To elucidate whether and how in patients with uremia on Hemodialysis (HD) the level of CRP as the marker of inflammation correlate with serum cholesterol, which is an index of nutrition in HD patients. The study was conducted on patients with End-Stage Renal Disease (ESRD), who were undergoing maintenance hemodialysis treatment with acetate basis dialysate and polysulfone membranes. After 12 h fasting, levels of serum cholesterol (Chol) and serum creatinin were measured. The total patients were 36 (F = 15, M = 21). The median patient's age was 43 years. The median length of the time patients had received hemodialysis 19 months. The median serum CRP was 8 mg L-1. The median serum cholesterol was 115 mg dL-1. In this study a significant inverse correlation of serum cholesterol with serum CRP was seen. It may be concluded that using the antilipid drugs in hemodialysis patients might be limited to specific cases and secondly more attention to use bio-compatible dialysis membranes which has a lower complement system activation to avoid more inducing the inflammation as well as more attention to the nutrition of HD patients needs.