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Abstract

A research work of herbal medicine viz. Neem leaf extract Azadirachta indica, nayantara leaf extract Catharanthus roseus and bitter melon fruit Momordica charantia juice with the patent drug gliclazide Comprid, Square Pharmaceuticals Bangladesh Ltd. were studied on blood glucose level, hematological parameters and on body weight in rats. Twenty-five apparently healthy adult rats were randomly divided into 5 equal groups namely A, B, C, D and E. One group group A was kept as control. The rest four groups B, C, D and E of rats were treated with gliclazide Comprid 4.5 mgkg bd. wt.day, neem leaf extract NLE 500 mgkg bd. wtday, nayantara leave extract NtLE 500mgkg bd. wt.day and bitter melon fruit juice 500 mgkg b. wt.day respectively for 14 consecutive days. Blood glucose levels were significantly P