Sleep quality in functional dyspepsia patients: A cross-sectional study from a tertiary care hospital in Karachi.

Article Information

Title: Sleep quality in functional dyspepsia patients: A cross-sectional study from a tertiary care hospital in Karachi.

Authors: Punhal Khan, Shahid Karim, Rajesh Kumar, Vishal Kumar, Afsheen Faryal

Journal: The Professional Medical Journal (TPMJ)

HEC Recognition History

Category	From	To
Y	2024-10-01	2025-12-31
Y	2023-07-01	2024-09-30
Y	2022-07-01	2023-06-30
Y	2021-07-01	2022-06-30

Publisher: Independent Medical College, Faisalabad- Pakistan

Country: Pakistan

Year: 2024

Volume: 31

Issue: 5

Language: English

DOI: 10.29309/TPMJ/2024.31.05.8017

Keywords: PainSleep qualityFunctional dyspepsiaEpigastricROME-IV Criteria

Abstract

Objective: To determine sleep quality among functional dyspepsia (FD) patients presenting to gastroenterology out-patient clinic in a tertiary care hospital. Study Design: Cross-sectional study. Setting: Department of Gastroenterology, Liaquat National Hospital, Karachi, Pakistan. Period: March 2022 to December 2023. Methods: FD diagnosis was established in view of ROME-IV criteria. Sleep quality was evaluated using Pittsburgh Sleep Quality Index PSQI scoring tool. A global score of 5 or more indicates poor sleep quality. Binary logistic regression was applied and odds ratio with 95% confidence level were figured out to assess relationship of patients' profile with FD. Results: In a total of 240 patients, the mean age was 37.3±6.5 years. There were 122 (50.8%) male patients. The most common dyspeptic feature was postprandial fullness (60.4%) followed by early satiety epigastric pain (50%) and epigastric burning (39.6%). Mean PSQI score was 14.7±3.5. Frequency of poor sleep quality among FD patients was 79.2%. None of the parameter was significantly associated with sleep quality except urban residence (p=0.005). Conclusion: Very high burden of poor sleep quality was found among FD patients. While most dyspeptic symptoms did not show a significant association with sleep quality, urban residence emerged as a notable factor.

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Research Objective

To determine sleep quality among functional dyspepsia (FD) patients presenting to a gastroenterology out-patient clinic in a tertiary care hospital.

Methodology

A cross-sectional study conducted at the Department of Gastroenterology, Liaquat National Hospital, Karachi, Pakistan, from March 2022 to December 2023. Functional dyspepsia was diagnosed using ROME-IV criteria. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), with a global score of 5 or more indicating poor sleep quality. Binary logistic regression was used to analyze the relationship between patient profiles and FD.

Methodology Flowchart

                        graph TD;
    A["Diagnosis of Functional Dyspepsia ROME-IV criteria"] --> B["Assessment of Sleep Quality using PSQI"];
    B --> C["Data Analysis"Binary Logistic Regression""];
    C --> D["Identify Associations between Patient Profile and Sleep Quality"];
    D --> E["Conclusion"];

Discussion

The study highlights a very high prevalence of poor sleep quality among functional dyspepsia patients. While most dyspeptic symptoms did not show a significant association with sleep quality in this study, urban residence emerged as a notable factor. The authors suggest that the complex interplay between sleep quality, dyspeptic symptoms, and environmental factors warrants further exploration.

Key Findings

Out of 240 patients, the mean age was 37.3±6.5 years, with 50.8% being male. The most common dyspeptic symptoms were postprandial fullness (60.4%), early satiety/epigastric pain (50%), and epigastric burning (39.6%). The mean PSQI score was 14.7±3.5, and 79.2% of FD patients reported poor sleep quality. Urban residence was the only parameter significantly associated with sleep quality (p=0.005).

Conclusion

There is a very high burden of poor sleep quality among functional dyspepsia patients. Urban residence was identified as a significant factor associated with sleep quality, whereas most dyspeptic symptoms did not show a significant association.

Fact Check

* The study enrolled 240 patients. (Confirmed in Results section)
* The mean age of the patients was 37.3±6.5 years. (Confirmed in Results section)
* 79.2% of functional dyspepsia patients reported poor sleep quality. (Confirmed in Results section)

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