DefinePK

Abstract

Objective: To determine the diagnostic accuracy of serum bilirubin levels as predictor of perforated and simple appendicitis. Study Design: Cross Sectional study. Setting: Surgical Unit Aziz Bhatti Shaheed Teaching Hospital Gujrat. Period: June 2019 to December 2019. Material & Methods: This study was conducted after approval of ethical committee and informed consent of patients. Serum Bilirubin level on photometric testing using 2,4-dicholoroaniline were determined. Histopathological examination was considered as a gold standard for diagnosing and categorizing patients as having acute appendicitis and acute appendicitis with perforated appendix. Serum Bilirubin levels and final histopathological reported were compared to determine diagnostic accuracy of serum Bilirubin levels. Results: The mean age of patient was 33.41±12.46 years. In this study 153(47.81%) patients were male and 167 (52.19%) patients were female. Sensitivity and specificity for Serum Bilirubin were 88.62% and 94.42%. The mean serum bilirubin level was 36.72±41.05 years. The minimum and maximum serum bilirubin level was 5.00 and 169.00. The positive predictive value was 90.83% and negative predictive value was 93% with diagnostic accuracy of 92.19%. Conclusion: Hyperbilirubinemia can be utilized for early diagnosis of appendiceal perforation and can identify the nature of appendicitis for better management.