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Abstract

Objectives: To determine the efficacy of topical nepafenac 0.1% eye dropsas compared toprednisolone acetate 1% eye drops in the management of postoperativeinflammation after cataract surgery. Study Design: Randomized controlled clinical study.Place and Duration of study: Pakistan air force hospital Rafiqui from Oct 2016 to Feb 2017.Patients and methods: Two hundred and forty eight eyes were randomly divided in two equalgroups. Patients received nepafenac 0.1% or prednisolone acetate 1% as single drop 8 hourlybeginning 1 day preoperatively, continued till 2 weeks post-operatively. Efficacy of the drugwill be considered if there is no anterior chamber reaction along with no aqueous flare after 2weeks of treatment. Results: 85.5% of cases resolved with topical nepafenac 0.1%as comparedto 88.7% that were cured with prednisolone acetate 1%. Pearson chi square test indicates thatthere is no statistical significant difference (p= 0.449) between the efficacy of two modes oftreatment. Conclusion: Nepafenac 0.1% eye drops are as effective as prednisolone acetate 1%in the prevention of postoperative inflammation with cataract surgery.