DefinePK

Abstract

Introduction: Early intervention among patients with prediabetes can prevent ordelay diabetes. Moreover, regression from prediabetes to normal glucose regulation has beenassociated with reduction in cardiovascular disease (CVD) risk. Estimate of prevalence of thiscondition is vital as diabetes is now a global epidemic requiring steps towards its prevention.Study Design: Descriptive study. Setting: Fatima Memorial Hospital & Medical & Dental CollegeLahore. Period: 1st February 2016 till 1st February 2017. Objective: To determine the prevalenceof pre-diabetes and associated risk factors and demographic features in our local populationusing HbA1c as a screening test. Material and Methods: The study population includes adults18 years and above who reported in hospital outdoor as well as employees, faculty membersand students. Subjects were included in the study after taking written consent. The statisticalanalysis was performed on SPSS version 23. Results: The number of subjects included was400. 138(34%) had HbA1c value in prediabetic range (5.7-6.4%) and 56 (14%) in diabetic range(>6.4%). Mean age of prediabetics was 41± 13, 34% were males and 66% were females, 27%were in age group less than 30 years. Their mean HbA1c was 5.9%. Above normal body massindex (BMI) was reported in 128 (93%) and positive family history of diabetes mellitus (DM) in135 (98 %) subjects (P value: 0.00). All females with history of Polycystic Ovarian Syndromeand Gestational Diabetes showed prediabetes. Conclusion: The prevalence of prediabetes issignificant in our studied population. It has strong association with family history of diabetes andabove normal BMI values. There are also a significant number of undiagnosed asymptomaticdiabetics in our population.