DefinePK

Abstract

Objective: To estimate the serum lipid profile of patients having different typesof senile cataract and compare them with that of the controls. Study Design: Observationalcase control study. Place of study: Tertiary care centre in the city of Lahore, Pakistan. Period:Six months. Methods: We selected fifty patients with senile cataract and fifty control individualsfrom tertiary care hospital of Lahore. History, ophthalmic and systemic examinations weredone. Fasting serum samples were taken for estimation of lipid profile from all the subjects.Results: In the patient group, female to male ratio was 1.63:1. 78% patients had Nuclearcataract, 16% had cortical and 6% had posterior sub capsular type of senile cataract. SerumTriglycerides, Cholesterol, LDL, HDL and VLDL of patients were compared with controls. Thep-value of cholesterol, LDL and HDL was non-significant. The p-value of triglycerides and VLDLwas significant. Conclusions: Serum Triglycerides and VLDL are modifiable risk factors in thedevelopment of senile cataract in Pakistani patients. Serum Triglycerides is the only lipid, whichhas shown consistent results related to cataract development in different parts of the world.Other lipids show variable results in different countries.