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First Case of Genetic Polymorphism in Uridine Monophosphate Synthase Gene in an Indian Holstein Bull


Article Information

Title: First Case of Genetic Polymorphism in Uridine Monophosphate Synthase Gene in an Indian Holstein Bull

Authors: Uma Gaur, Tejaswini G. Sathe, Arpita Roy, Rajesh K. Patel, P. S. Satish Sunkara

Journal: International Journal of Veterinary Science

HEC Recognition History
Category From To
Y 2023-07-01 2024-09-30

Publisher: Unique Scientific Publishers

Country: Pakistan

Year: 2013

Volume: 2

Issue: 1

Language: English

Keywords: DNAPCR-RFLPHolstein cattleDUMPS

Categories

Abstract

The present study investigated the occurrence of an autosomal recessive genetic disease, bovine deficiency of uridine monophosphate synthase (DUMPS), in Indian Holstein cattle. The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was performed on routine screening of 86 Holstein bulls station at various part of the country to identify carriers of the disease. One of the bulls was found carrier of DUMPS. It is therefore recommended to screen breeding bulls for their breed-specific genetic disorders before they are inducted in artificial insemination programmes, to minimize the risk of spreading.


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