DefinePK

Abstract

A study was undertaken to compare the efficacy of different therapeutic protocols in sixty four ketotic dairy cows. All the ketotic dairy cows were equally divided into group 1st, 2nd, 3rd and 4th. Animals in 1st group received 25% dextrose intravenously two pints and gluconeogenic precursors fortified with B-complex vitamin 100 ml twice orally for four days, animals in 2nd group received 25% dextrose intravenously two pints and insulin 200 IU subcutaneously for two days, animals in 3rd group received liquid glucose and sodium bicarbonate orally for four days, and animals in 4th group received 25% dextrose two pints intravenously and 5ml isoflupredone acetate intramuscularly for three days respectively. The mean recovery time (days) was recorded highest in group 4th (2.3±0.26) followed by 2nd (2.6±0.16), 1st (3.3±0.26) and 3rd (3.9±0.23). Therefore, during the current study glucose administration either parentally or orally in combination with gluconeogenic precursors fortified with B-complex vitamins, insulin, sodium bicarbonate and isoflupredone acetate gave excellent recovery rate.