DefinePK

Abstract

Three different types of Newcastle disease (ND) vaccines were compared in the study on the basis of their post vaccinal antibody titres in backyard poultry. A total of one hundred domestic poultry birds were selected and divided into five equal groups (A to E). All the groups except Group E (absolute control) were primed with ND La Sota vaccine at 7th day of age. At day 21 groups A, B, C were boosted with ND La Sota, Mukteswar (R2B strain) and ND killed vaccine (oil based) respectively, while group D was kept as booster control. Antibody titers were compared by using the Haemagglutination Inhibition (HI) Test. Six weeks cumulative mean titres (CMT) recorded in groups A, B, C, D, and E were 36.22, 51.22, 57.97, 15.23 and 5 respectively. Statistical analysis showed that the CMT of groups vaccinated with the booster dose of Mukteswar (R2B strain) and oil based vaccines were significantly higher (P< 0.05) from the group vaccinated with the live La Sota vaccine. The results indicated that booster vaccination with Mukteswar (R2B strain) or oil based vaccine should be used rather La Sota.