DefinePK

Abstract

The current study was planned to make antigens of sonicated Serratia marcescens and study its result on the mice blood cells for the first time in Iraq. For this purpose, 24 mice divided into four groups. The first group was vaccinated with killed whole cell sonicated antigens of Serratia marcescens (KWCSA-SM) (1000 µg/ml) Subcutaneously. Second group was immunized with killed (KWCSA-SM) (500 µg/ml) S/C. Third group was immunized with whole cell Serratia marcescens (1.5×108cfu/ml), 5th group was injected by P.B.S. (pH7.2) as negative control group. Blood cells showed variances in the hematological changes between the 1st group and the other immunized groups associated with negative control group that show no hematological variations in their cells. Statistical study exposed significant differences between groups (P> 0.05). The aim of this study is to observe the effect of the two antigens concentration on the hematological changes of blood cells for the first time in Iraq.