DefinePK

Abstract

In the present study we investigated the pathogenicity of the isolated salmonellae to one day old specific pathogen free (SPF) chicks. The selected isolates were based on the most antibiotic resistance strains. The antimicrobial susceptibility test revealed that 46% of the isolated salmonellae were resistant to amoxicillin, 52% to ampicillin, 46 % to cefotaxime, 86% to ciprofloxacin, 82% to clindamycin, 64% to doxycycline, 74% to erythromycin, 62% to gentamicin, 96% to lincomycin, 54% to neomycin, 92% to norfloxacin, 22% to oxytetracycline and 18% to streptomycin. Two hundred and ten, one day old SPF chicks were used to determine clinical signs and mortality caused by Salmonella isolates; Newport, Kentucky, Enteritidis, Infantis, Derby and Typhimurium isolated from broiler poultry flocks. Re isolation of salmonellae was done from dead birds of each groups, (samples taken from each dead chick were liver, heart, spleen and intestine samples). Every week, 5 serum samples were taken randomly from each group for serological test to determine salmonella antibody for each serotype.