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Abstract

This work measured the status of oxidative stress (OS) biomarkers during the periparturient period in dromedary camels with ketosis. The Qassim University Veterinary Hospital in Saudi Arabia registered 17 diseased female dromedary camels. They underwent examination because of the gradual decline in body condition during the first three months post-parturition. Ten clinically healthy female dromedary camels were enrolled in this study as controls. For serum harvesting, collected a 7mL blood sample in plain tubes from each camel. Malondialdehyde (MDA) as lipid peroxidation biomarker and stress indicators, including catalase (CAT), Glutathione (GSH), and superoxide dismutase (SOD), were determined in the sera. In addition, lipid profiles that included cholesterol, triglycerides (TG), high-density lipoproteins (HDL), and low-density lipoproteins (LDL), as well as ?-hydroxybutyric acid (?HBA), were measured in the same samples. Compared to the values in the controls, the MDA was significantly higher (P<0.001) in the diseased group. However, the GSH value was significantly lower in the diseased camels compared to the healthy ones (P<0.01). Similarly, the SOD value was lower in the diseased animals than in the healthy camels (P<0.001). The ?HBA values were significantly higher in the diseased group than in healthy females (P<0.01). The cholesterol, TG, and LDL values were more elevated in the diseased group than in the healthy animal group (P<0.001). On the contrary, a statistically significant lower HDL value (P<0.001) was found in the diseased group compared to the healthy animal group.