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Abstract

Surveillance for genetic markers of adaptation of SARS-CoV-2 in dogs and cats could help to predict the risk of variant emergence, that resulted from virus adaptation to the new host. The Delta variant of SARS-CoV-2 collected from dog and cat is of high interest, since this variant caused global major cases and fatality during the pandemic. All complete and high coverage sequence data of Delta variant of dog and cat origin, as well as samples of human origin SARS-CoV-1 were downloaded. All selected sequence data were subjected to Clustal Omega alignment. Evolutionary history was inferred by using the Maximum Likelihood method using Mega11. Species-specific markers indicating a probable species adaptation of the pandemic SARS-CoV-2 in dog and cat could not be identified. The markers found in many dog and cat samples is confirmed to be location specific markers that occurred in human origin virus.