DefinePK

Abstract

A 10-year-old male mixed breed dog was referred for evaluation with ascites, vomiting and progressive weight loss. Following a clinical and cardiological examination, an ultrasound was performed with findings consistent with a mass at the base of the heart. Computed tomography showed that the mass involved cranial aorta, aortic arch, pulmonary artery, cranial vena cava and atrial wall, as well. Multiple pulmonary nodules and lymph node involvement were confirmed. Pericardiectomy and incisional biopsy were performed via left lateral thoracotomy. Histopathology and immunohistochemistry revealed an ectopic follicular thyroid carcinoma. Primary thyroid carcinoma was ruled out. The patient remained stable for 300 days following combined oncology therapy, which included chemotherapy and tyrosine kinase inhibitors, with no significant hemodynamic changes or respiratory failure.