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Abstract

This study examined the effects of Moringa oleifera Lam leaf extract, using ethanol solvent at different doses, supplemented with additional minerals and vitamins, on the development of ovarian follicles in female Mus musculus. Thirty-six five-week-old female Mus musculus having reproduction disorder were used in the current experiment. The experimental design was a completely randomized design, with four different levels of M. oleifera Lam leaf extract (T1=4mg/kg Live weight (LW), T2=8mg/kg LW, T3=12mg/kg LW, and T4 or control=0 mg) fed to the animals. The data were analyzed using one-way ANOVA in SPSS and the histopathological analysis was descriptively conducted. The results indicated that treatments T1, T2, and T3 ensured adequate feed and high daily weight gain in Mus musculus. Histopathological examination of the ovaries revealed that a 4mg/kg LW dose of M. oleifera Lam leaf extract was sufficient to promote ovarian development and normalize the reproductive cycle.