DefinePK

Abstract

Candida -induced infections affect millions of women around the world. Therefore, the purpose of this review is to provide a comprehensive analysis of the role of antifungal therapy and probiotics in managing one such infection, vulvovaginal candidiasis (VVC). The study employed a systematic review method to retrieve relevant articles from databases such as PubMed, MDPI, Scopus, and ResearchGate, using specific search criteria. The findings highlight the effectiveness and limitations of traditional antifungal treatment, the emergence of novel treatments targeting new biological pathways, and the potential of probiotics as adjunctive therapy. It is concluded that while traditional antifungals remain fundamental, resistance issues necessitate ongoing development of novel agents. Additionally, alternative therapies hold promise in enhancing treatment outcomes and maintaining vaginal health. The multifaceted approach in VVC treatment highlights the importance of integrating various infection control and treatment strategies into a more effective and holistic approach. Keywords: Candida sp.; Vulvovaginal candidiasis; Antifungal agents; Probiotics