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In-vitro study on antioxidant status of Zinc NPs and crude extract of Ayurvedic herbal formulation


Article Information

Title: In-vitro study on antioxidant status of Zinc NPs and crude extract of Ayurvedic herbal formulation

Authors: Jaafar Faez Kadhim Alsadooni, Sura Razzaq Khudhair

Journal: Advancements in Life Sciences

HEC Recognition History
Category From To
X 2023-07-01 2024-09-30
X 2022-07-01 2023-06-30
Y 2021-07-01 2022-06-30
Y 2020-07-01 2021-06-30

Publisher: Centre of Excellence in Molecular Biology

Country: Pakistan

Year: 2024

Volume: 11

Issue: 2

Language: en

DOI: 10.62940/als.v11i2.1931

Categories

Abstract

Background:   To create and evaluate cutting-edge therapeutic composition on biosynthesized nanoparticles exhibiting varied biological activity, nanotechnology is a novel and forward-thinking method. Increased antioxidant activity decreased toxicity to free radicals as well as cancer cells, and other benefits are achieved carefully by regulating the form and nanoparticle dimensions. Methods:  Nanostructures biosynthesized utilizing Liv-Pro-08 AHF showed a strong antioxidant effect. The creation of novel and more efficient antioxidants may benefit from the usage of nanoparticles. It is noteworthy that the resulting nanoparticles exhibit more biological processes than the extract. This research aims to calculate if there are any noticeable differences in the behaviour of leaf extracts and the many nanomaterials obtained from the aqueous-based separation of Liv-Pro-08 Ayurveda herbal-based formulations. Results:  Several in-vitro free radical scavenging experiments were used to determine whether or not Liv-pro-08 nanoparticles possessed any antioxidant properties. Zinc nanoparticles generated from Liv-pro-08 ayurvedic formulation demonstrated dose-dependent suppression of DPPH, as well as concentration-dependent lowering power potential, indicating that the nanomaterials contain free radical scavenging capability to produce the antioxidant effect. Conclusion:  Nanoparticles might be useful for the development of newer and more potent antioxidants. It is worth mentioning that the resultant nanoparticles possess an elevated biological activity in comparison to the extract. The data represented in our study contribute to a novel and unexplored area of nano materials as alternative medicine. Keywords: Antioxidants; Biosynthesis; Leaf extract; Liv-pro-08; Zinc   


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