DefinePK

Abstract

Objectives: To assess the incidence of malignancy in patients with Multinodular goiter in southern Punjab. Study design:A retrospective study. Place & Duration of study: Department of General Surgery, Sheikh Zayed Medical College & Hospital Rahim YarKhan, from April 2010 to May 2012. Patients and Methods: All patients were presented in OPD with history of Multinodular goiter onclinical examination or USG neck. FNAC of any dominant nodule or suspicious nodule on USG neck was performed. All patients wereoperated & total thyroidectomies were done in all patients irrespective of the age. We sent all specimens for histopathological examinationand reports were collected from department. The whole information collected was entered in a pre designed proforma. Results: During 2years period, total 141 patients of thyroid disease were seen in OPD out of which 98 patients have Multinodular goiter. Histopathology ofthese patients showed 10 malignancies & 88 benign. Most of the patients that turned out to be malignant belong to 41-50 years agegroup. 7 patients were female and 3 were male. Among the malignancies 50% were papillary, 30% were follicular, and 10% wereanaplastic carcinoma & lymphomas each. Conclusions: Multinodular goiter (MNG) is the commonest indication of thyroidectomy iniodine deficient areas of Pakistan. This study concludes that don’t consider MNG as a benign disease anymore until proved otherwise.