DefinePK

Abstract

N-acyl lysine is a surface-active substance that can reduce interface tension between oil and water. N-acyl lysine was synthesized by calcium oxide amidification of lauric acid and lysine. The study aims to increase lauric acid conversion by observing the effect of substrate ratio, catalyst amount, and solvent ratio, through the preparation and observation of mathematical models using Box Behnken Design and Response Surface Methodology. Optimal conditions are observed in the ratio of lauric acid to lysine 1:2; 1:3; 1:4, catalyst amount 3%; 5%; 7%, and a solvent ratio to lauric acid 1:1; 1:2; 1:3. In this optimal condition, the conversion of lauric acid will increase by more than 80%. The variable amount of catalyst showed a more significant effect in increasing lauric acid conversion. The results showed that all three variables affect the percent conversion with an R2 of 90.32%.