DefinePK

Abstract

The research carried out is related to developing the process of making surfactants based on amino acids from renewable natural resources. At this stage, the potential for hexadecanoic acid (HA) and L-lysine (L) to be synthesized into a surfactant based on the amino acid N-acyl L-lysine was observed in a stirred tank. For this reason, the research was planned with a specific objective to examine the effect of the substrate ratio, solvent ratio, and catalyst concentration on amide recovery using the Box-Behnken Design. Furthermore, analysis of the interaction effect of the research variables is carried out, compiling an optimization equation model and assessing the optimum reaction conditions to obtain the maximum conversion response. The product purification process is carried out by adding 5 ml of 10% citric acid and then filtration with filter paper then heated at 90 °C to evaporate the remaining solvent. The optimum conversion percentage obtained is 78.084%, which can be generated through six composition options with the same desirability value, 0.851. Among the six options, the substrate ratio of 2.956 (L/HA), the solvent ratio of 2.0 (MS/S), and catalyst concentration of 5% (w/wHA) were selected as the best process variable values at a reaction temperature of 65 °C and reaction time 2 h.