DefinePK

Abstract

Biodegradable surfactants can be obtained from natural lipo amino acids from renewable raw materials. Stearoyl lysine is an environmentally friendly surfactant and was synthesized by amidification reaction of octadecanoic acid and lysine. Evaluated for their reaction variables, such as catalyst ratio (A), substrate ratio (B), and solvent ratio (C), to the amount of octadecanoic converted to stearoyl lysine has been optimized using Box Behnken Design. Significantly, variables A, C, AC, BC, A^2, B^2, and C^2 had a significant effect on the response, namely the conversion of octadecanoic acid. However, the quadratic model needs to be reduced because the difference between the adjusted R-squared and the predicted R-squared is more than 0.2.