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Abstract

Objective: To determine the survey on comparing fasting Homocysteine levelsamong healthy adults, diabetic and non-diabetic cardiac patients.
Methods: Using Purposive sampling method, Comparative analytical study was conducted in Rawalpindi institute of cardiology between 6 June to 15 July 2016 and compromised of healthy adults, diabetic cardiac and Non-diabetic cardiac patients between age of 20 to 60, blood samples were drawn during last week of Ramadan and then examined forhomocysteine level. Additional information like age, ESR, lipid profile and Leukocytes count were also Analyzed.
Results: Of the 93 subjects, there were 30(32.3%) each in healthy adults and diabetic cardiac patient groups A and C respectively but 33(35.5%) patients were in non-diabetic cardiac patients group B. The mean ageof group A, B and C were 51.3+5.6 years, 56.73+9.35 years and52.4+9.07 years respectively. The mean values of Homocysteine were 12.3, 14.39 and 15.17 among group A, B and C respectively. The mean values of LDL were 2.90, 3.58 and 3.35; for HDL 1.09, 1.19, and 1.19 among group A, B and C respectively. The mean values of Triglycerides were 1.45, 1.96 and 2.07; for Cholesterol4.72, 5.71 and 5.52 among group A, B and C respectively.
Conclusions: We may concluded that fasting may have beneficial effects on maintaining homocysteine levels for among healthy adults, diabetic non cardiac patient as their mean values were within normal range as well as on diabetic cardiac patient but that were near to normal.
Keywords: Homocysteine, Fasting, Cardiac Patients, Diabetes, Healthy Adults.